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cenobamate will improve the level or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Closely. Consider a dose reduction of CYP2C19 substrates, as clinically acceptable, when made use of concomitantly with cenobamate.diazepam increases levels of lomitapide by impacting hepatic/intestinal enzyme CYP3A4 metab

Reserve concomitant prescribing of such medications in people for whom other treatment solutions are insufficient. Limit dosages and durations to the bare minimum necessary. Keep an eye on intently for indications of respiratory despair and sedation.Infants born to moms using benzodiazepines late in pregnancy described to knowledge indications of s